Dindolyl Methane, or DIM as it is commonly referred to, is a popular supplement for bodybuilders as well as other people who want to increase muscle growth. Recent studies have shown that DIM could pose health risks. For instance, DIM can cause serious liver damage when consumed in excess. Kidney damage is also a concern, and may result in kidney failure. The long-term health risks associated with DIM have many bodybuilders and athletes ask the question: should I supplement my diet with supplements with DIM?
Most people use diindolylmethane as a supplement to increase the production of testosterone. Testosterone has been shown to act as an androgen, meaning that it can trigger hormonal changes in tissues. Studies have shown DIM to mimic the effects both of testosterone and other hormones. Some manufacturers have added diindolylmethane (DIM) to their products to increase their appeal to males because men produce more testosterone than women. Men will react to products that mimic natural testosterone.
In the end, many companies market DIM as a cancer suppressor. It’s true that diindolylmethane does decrease the growth of tumors in laboratory animals, but these animals were given the drug, not taken orally. In order for humans to experience the same result diindolylmethane needs to be taken in high doses for longer periods of time. Additionally, even though the animals studied did remain cancer-free for several years however, they all suffered from liver disease at some point, likely due to too much diindolylmethane being present in their bodies. A medical practitioner can give you more information about the way DIM functions within the body.
The only way to demonstrate that DIM is effective in treating breast carcinoma is to do an experiment where cells from healthy breast cells are exposed to high doses of diindolylmethane over an extended period of time. There are pros and cons to using DIM, as with any chemical. The ability to mimic hormones is one of the advantages. This means that you could make insulin, which could inhibit cancer cell proliferation. The disadvantages are that diindolylmethane can also produce a potentially damaging chemical known as DMSO. Read more about dim diindolylmethane supplement here.
One of the most commonly used claims made for diindolylmethane as an option for treating various health problems is that it can act as a natural, antibacterial, anti-fungal and anti-cancer agent. The National Institute of Health, in their exhaustive study of supporting data concluded that there was no basis for these claims. According to the Institute of Chemical Technology, there were no experiments performed to support this assertion. The Institute of Chemical Safety, conducting an in-depth study of the safety profile for the firestone concluded that the evidence offered by pharmaceutical companies on the benefits of diindolylmethane for humans were not completely reliable.
Van der Goes and. and. published their findings in the May 2021 issue of the Journal of Toxicology and Environmental Health. Van der Goes, et al., highlighted the potential risks of diindolylmethane use, including allergic reactions to the skin, asthma attacks as along with headaches, dizziness and respiratory problems. They also stated that the recommended daily allowance for this chemical is 0.2 milligrams, which is about one tenth of a teaspoon. It isn’t clear what the concentration is when it is compounded with other compounds. Because this substance has not been thoroughly tested, it is not considered safe at any level.
The abstract of the view shows the use of diindolylmethane in cancer treatment is based on the notion that intracellular inhibition of pyruvate metabolism by flavenoids can be inhibited and prevents accumulation of oxalates and pyruvate metabolites in renal tubule cells. The toxicology studies of the drug metabiplicate have not proven that this chemical can cause overdose. In June 1996, the Food and Drug Administration approved the drug as a prescription drug. According to the FDA the manufacturer of firestone tincture is currently in the process of conducting two major studies – one in Europe and the other in the United States.
The view abstract also shows that diindolylmethane’s usage in the treatment of cancer is based on the principle of inhibiting intracellular inhibition through flavenoids of pyruvate metabolism and thus preventing the accumulation of adenine and oxalates within renal tubule cells. Metabiplicate toxicology studies on the drug have not demonstrated that this chemical is able to cause overdose. In June 1996, the Food and Drug Administration approved the drug as a prescription drug. According to the FDA the company that makes firestone Tincture is currently conducting two major trials in Europe and the United States. According to FDA, the FDA states that the maker of firestone Tincture is currently completing two major trials in Europe and one in the United States.